Let’s discuss the biological clock that regulates cholesterol and oxidation levels in the blood.
What regulates cholesterol in the body? A new study conducted by Professor Michael Aviram of the Technion and Rambam Medical Center will appear in the Journal of Horticulture.
The study examined cholesterol levels in healthy subjects, patients with hypercholesterolemia (before and after treatment with statins or pomegranate extract), and diabetic patients (before and after treatment with metformin or pomegranate extract).
It was found that peak levels of blood lipids and oxidative stress in healthy people are recorded in the afternoon. In contrast, patients with hypercholesterolemia or diabetes show peak levels at night.
A circadian rhythm pattern was detected among healthy subjects during the day.
Professor Aviram states, “The practical significance of these findings is that we need to use medication or nutritional therapy intelligently. We must instruct patients to take medications so that they work while their lipid levels and oxidative stress are at their peak.”
Adjusting treatment times to align with blood test patterns can optimize treatment goals, such as delaying the development of atherosclerosis. This delay may prevent heart attacks or strokes.
Professor Michael Aviram is the Director of the Lipid Research Laboratory at the Technion’s Rappaport Faculty of Medicine and the Rambam Medical Center.
